Stem Cell Research Articles

Stem cell therapy is a fascinating field of medicine with enormous amounts of research devoted to its advancement. We have pulled together a group of relevant scientific publications for those who are interested in a deeper review. Below is a list stem cell research articles to help you gain additional insight into the ongoing studies. Research conclusions bring clarity into persisting stem cell myths.

Adipose-Derived Adult Stem Cells and New Technique for Intracavernosal Injection for Erectile Dysfunction: Novel Approach to Treat Diabetes Mellitus. Erectus Shot Technique

PUBLISHED in Integrative Molecular Medicine Medicine, 2016, Vol 3(2)   AUTHOR Carlos Mercado, MD

Erectile Dysfunction (ED) affects 10 percent of the population worldwide. In 1995 it was estimated that 152 million men were affected by ED. It is estimated that by 2025 352 million of population worldwide will be affected. Currently there is not available treatment that can restore or regenerate the tissues in the corpus cavernosum or arterial system tthat will cure ED a 20 percent failure rate with present therapies and high rate of drop out in patients with ED due to radical prostatectomy and post radiation. Testosterone eplacement is the only independent risk factor that might help endothelial dysfunction and consequently ED. Adipose tissue is abundant and easy to collect from a miniliposuction. The procedure consists in collecting a lipoaspirate of 60 ml. No general Anesthesia is required. It is an outpatient procedure. Adipose tissue is processed using a non animal collagenase enzyme. Stromal vascular fraction (SVF) is isolated. Blood is obtained through a venipuncture. Platelet rich-plasma (PRP) is obtained. The SVF is suspended in PRP. The mixture is injected into the corpus cavernosum using our designed protocol for injection.

Four types of patients: DM, ED due to prostatectomy and radiation, Peyronie’s disease, and ED organic cause/aging/vascular. Patients filled out the intensity score questionnaire before and after procedure. Both reported better erections in the morning, firmer, and better response to PDI5 inhibitors for which they were not responders prior to the treatment. This might be due to stem cells induced regeneration of the cavernous nerve and endothelial cells enhancing the nitric oxide production hence improved response to PDI-5 inhibitors.

Abandoning Microfracture of the Knee: Has the Time Come?

PUBLISHED on The Journal of Arthroscopic and Related Surgery, 2015   AUTHORS Jack M. Bert, M.D.

Regenerative Repair of Damaged Meniscus with Autologous Adipose Tissue-Derived Stem Cells

PUBLISHED on BioMed Research International by Jaewoo Pak et al., 2014.   AUTHORS Jaewoo Pak, Jung Hun Lee and Sang Hee Lee.

Intra-Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: a Proof-of-Concept Clinical Trial

PUBLISHED on Wiley Online Library by AlphaMed Press, 2014.   AUTHORS Jo CH, Lee YG, Shin WH, Kim H, Chai JW, Jeong EC, Kim JE, Shim H, Shin JS, Shin IS, Ra JC, Oh S, Yoon KS.

 KEYWORDS Adipose-tissue derived mesenchymal stem cells; Cartilage regeneration; Intra-articular injection; Osteoarthritis.

Stem Cell Therapy Following Meniscus Knee Surgery May Reduce Pain, Restore Meniscus

PUBLISHED on Digital Journal by The American Academy of Orthopaedic Surgeons (AAOS), 2014.

Adult Human Mesenchymal Stem Cells Delivered via Intra-Articular Injection to the Knee Following Partial Medial Meniscectomy

PUBLISHED in The Journal of Bone & Joint Surgery Inc., 2014.   AUTHORS ; ; ; ; ; .

You May Not Be Better Off After Knee Surgery


Arthroscopic Partial Meniscectomy versus Sham Surgery for a Degenerative Meniscal Tear

PUBLISHED in The New England Journal of Medicine by the Finnish Degenerative Meniscal Lesion Study (FIDELITY) Group, 2013.   AUTHORS Raine Sihvonen, M.D., Mika Paavola, M.D., Ph.D., Antti Malmivaara, M.D., Ph.D., Ari Itälä, M.D., Ph.D., Antti Joukainen, M.D., Ph.D., Heikki Nurmi, M.D., Juha Kalske, M.D., and Teppo L.N. Järvinen, M.D., Ph.D.

Treatment of Knee Osteoarthritis with Autologous Mesenchymal Stem Cells: a Pilot Study

PUBLISHED in The Transplantation Journal, 2013.   AUTHORS Orozco, Lluis; Munar, Anna; Soler, Robert; Alberca, Mercedes; Soler, Francesc; Huguet, Marina; Sentís, Joan; Sánchez, Ana; García-Sancho, Javier

Millennium Medical Technologies – Statement of Position towards FDA’s Stance on Stem Cell Therapy

 PUBLISHED on, 2013.   AUTHORS David Angeloni

No Such Thing as Stem Cells in a Bottle

PUBLISHED in Philippine Daily Inquirer, 2013.   AUTHORS Cheche V. Moral

FDA Regulations of Stem Cell Therapy

PUBLISHED on, 2014.

Adipose-Derived Stem Cells for Regenerative Medicine

PUBLISHED in Circulation Research by American Heart Association, 2007.   AUTHORS Jeffrey M. GimbleAdam J. Katz, Bruce A. Bunnell

KEYWORDS adipose tissue, adult stem cells, bone marrow stromal cell, differentiation, tissue engineering

Adipose-Derived Stem Cells: Characterization and Current Application in Orthopaedic Tissue Repair

PUBLISHED in Experimental Biology and Medicine, 2008.   AUTHORS Hazel Tapp, Edward N. Hanley Jr., Joshua C. Patt, Helen E. Gruber

KEYWORDS adipose-derived stem cells, orthopaedic tissue regeneration, cell-surface markers, differentiation

Human Adipose Stem Cells: Current Clinical Applications

PUBLISHED in Journal of American Society of Plastic Surgeons, 2012.   AUTHORS Gir, Phanette M.D.; Oni, Georgette M.D.; Brown, Spencer A. Ph.D.; Mojallal, Ali M.D., Ph.D.; Rohrich, Rod J. M.D.

Human Adipose Tissue Is a Source of Multipotent Stem Cells

PUBLISHED in Molecular Biology of the Cell, 2002.   AUTHORS Patricia A. ZukMin ZhuPeter AshjianDaniel A. De UgarteJerry I. HuangHiroshi MizunoZeni C. AlfonsoJohn K. FraserProsper Benhaim and Marc H. Hedrick

President Obama and the Embryonic Backfire

PUBLISHED on Huffington Post, 2013.   AUTHORS Robin L. Smith

Adult Mesenchymal Stem Cells: an Innovative Therapeutic for Lung Diseases

PUBLISHED in Discovery Medicine, 2010.   AUTHORS Tracey L. Bonfield, Arnold I. Caplan

Potential Role of Stem Cells in Management of COPD

PUBLISHED in International Journal of COPD, 2010.   AUTHORS Tillie L Hackett, Darryl A Knight, and Don D Sin

 COPD, stem cell therapy, epithelial repair, regenerative medicine

Stem Cell Therapy of Osteoarthritis Using Stromal Vascular Fraction Cells

PUBLISHED in The Journal of Cell Therapy, 2013.   AUTHORS J. Michalek, Z. Kristkova, J. Skopalik, Z. Dudasova, A. Darinskas, R. Moster

Stem Cell Orthopedic Specialists Find New Stem Cell Therapies Can Treat Chronic Conditions

PUBLISHED on PRWeb, 2013.

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